yes some of the little so and so's recognise the name of removal software and wont allow you to run/ install it.
one machine i found i had to rename the .exe file as test or something like that to get it through.
Normally the best method is to have you handy bootable Linux Live CD and usb hard drive,
run from linux get all of the data off that you need then reinstall the OS again ( and Again , and Again

)
I do the IT for the company i work for as a secondary job with all of the AV hogging the resources i wish we could dump windows and move to something less virus prone. But we need the software vendors do port there products over or allow them to be run from an internal web server.

we also run unix workstations so not many issues with them ( aprt from you can't buy unix workstations any more even though the cad systems are still being sold that run on them ( Catia V4)